![]() ![]() Symptoms and signs of AW include mild to moderate tremors, irritability, anxiety, or agitation, among others. Heavy drinkers suddenly decreasing their alcohol consumption or abstaining completely may experience alcohol withdrawal (AW). ![]() ICMR bulletin estimated 62 million alcoholics in India which is as big as that of the population of France. Increase is more in countries where use of alcohol is traditionally less on population level and methods of prevention, control or treatment are not easily available. Globally alcohol consumption has increased in recent decades, with most of the increase in developing countries. The World Development Report found that the alcohol related disorders affects 5-10% of the world’s population each year and accounted for 2% of the global burden of disease. Full text articles, meta-analyses, systematic reviews and randomized controlled trials were obtained from this list and were considered for review.Īlcohol use is a pervasive problem that is taking an increasing toll on the world’s population. Articles not relevant to clinical utility and management were excluded based on the titles and abstract available. We searched Pubmed for articles published in English on ‘Alcohol withdrawal syndrome’ in humans during the last 10 years. This article aims to review the evidence base for appropriate clinical management of the alcohol withdrawal syndrome. Symptom triggered regime is favoured over fixed tapering dose regime, although monitoring through scales is cumbersome. Supportive care and use of vitamins is essential in the management. Others, such as anticonvulsants, barbiturates, adrenergic drugs, and GABA agonists have been tried and have evidence. Benzodiazepines have the largest and the best evidence base in the treatment of alcohol withdrawal, and are considered the gold standard. The severe complicated alcohol withdrawal may present with hallucinations, seizures or delirium tremens. Alcohol withdrawal syndrome ranges from mild to severe. Alcohol withdrawal symptoms are a part of alcohol dependence syndrome and are commonly encountered in general hospital settings, in most of the departments. Alcohol dependence is an increasing and pervasive problem. ![]()
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